The present study was undertaken to test the chemopreventive effects of one herbal medicinal plant, Indigofera aspalathoides, on chemically. The treatment by I. aspalathoides on fibrosarcoma bearing rats has improved the levels Indigofera aspalathoides (I. aspalathoides) treatment for rat arthritis is. Abstract: Civarvembu/ Sivanimba is botanically equated to Indigofera aspalathoides Vahl ex. DC. (Leguminosae). The plant is prescribed for eczema, psoriasis.

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Tumors which appeared in about 4 weeks after implantation were highly localized and were maintained by serial transplantation. The reversal of glycoprotein levels to almost normal after the treatment of Indigofera aspalathoides may be due to its potent antitumor activity.

This page was last edited on 29 Novemberat But in Group III drug-treated animals, these protein levels were reverted back to near normal condition as compared with Group II fibrosarcoma animals.

We declare that we have no conflict of interest. The levels of hexose, hexosamine, and sialic acid in liver and kidney of control and experimental animals. Selva kumar S and Karunakaran CM et al. Absence of significant variation in weights of body, liver and kidney in drug control animals reveals the non toxic nature of the plant drug. Notes Comments Background The research is a descriptive study of the effect of I.

The activity levels of nucleic acids such as total DNA and RNA and hexose, indigofeea, and sialic acid in liver and kidney of treated rats were used to monitor the chemopreventive role iindigofera the plant extract. At the lower dosages assayed, no signs of illness were noted at any time of post challenge.

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It seems that the minor components of the extract might synergistically act along with the active principle, thus probably reducing the intensity of treatment, which otherwise could have caused toxicity. A general description, with any kind of information about the taxon. During the entire period of our study no difference in food and water intake was observed among the groups of animals.


ALP is membrane bound and its alteration is likely to affect the membrane permeability and produce derangement in the transport of metabolites.

Materials and Methods 2. Echitamine chloride, a plant alkaloid has been reported to inhibit tumor growth as compared to untreated tumor [24].

Indigofera Aspalathoides Herb Uses, Benefits, Cures, Side Effects, Nutrients

The inorganic material was precipitated and filtered off. The protective effect of I.

Estimation of free fatty acid This was performed by the method of Hron and Menahan [23]. This plant is used for the treatment of leprosy, syphilis, and various skin diseases [ indigovera ].

Chemical Constituents of Indigofera Aspalathoides Vahl. Ex. DC.

In recent times focus on plant research has increased around the world and a large body of evidence has been collected to show the immense potential of medicinal plants used in various traditional systems of medicine.

Chemotherapy, although being a major treatment modality used in the control of advanced stages of malignancies, exhibits severe toxicity on normal tissues [ 8 ].

Gluconeogenesis from alanine in patients with progressive malignant disease. The extract of this plant causes disappearance of some symptoms by giving subjective and objective improvements. This was done by the method of Parekh and Jung [21]. The disease cancer will become the leading cause of mortality among human population [ 1 ]. Life cycles are treated in the field for Life Cycle.

To find out the anticancer effect of Indigofera aspalathoides I. The residue was once again scrapped from the filter paper and homogenized with 7 mL of chloroform: Determination of nucleic acid in tissue.


Such type of malignant cancer commonly involves deep tissue extremities, trunk, neck and head. I would suggest the following experiments in future after publishing this preliminary report: Plants have played a major role in treatment of various diseases of animals and humans since time immemorial.

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The tumor was minced and suspended in normal saline. Can include ecosystem services.

The wound treated with plant drug showed higher rate of wound contraction, increased level of Hydroxy proline, Hexosamine, SOD, Ascorbic acid and decreased levels of Lipid peroxides as well as histopathological studies also showed progressive collagenation and few macrophages compared to the control rats Since ancient times, herbal drugs are used in traditional system of medicine such as Siddha, Ayurvedaand Unani.

The levels of antioxidant enzymes CAT, SOD and GPx, were corrected to near normalcy in fibrosarcoma-bearing animals by treating with aqueous extract of Indigofera aspalathoides. The chemo preventive effects of Indigofera aspalathoides was studied on chemically induced carcinogenesis in rats. Many of the drugs sold today are derived from plants and simple synthetic modifications were done to obtain newer molecules.

The allopathic system of medicine adopted many medicinal plants to derive newer molecules for challenging diseases. The tumor is a large, firm, and pale mass without any capsule and infiltrates into the surrounding tissues. Received Nov 7; Accepted Dec 7.